Detection of Chlamydia trachomatis Immunogloblins in Seminal Plasma by Microimmunofluorescence Test and Their Effect on Semen Parameters of Infertile Males in Iraq
نویسندگان
چکیده
Background: There is controversy over the role of asymptomatic genital tract infection of Chlamydia trachomatis (C. trachomatis) in the etiology of male infertility. Aim of the Study: Detection of chlamydia antibodies in seminal plasma of infertile men and its effect on semen parameters. patients and Methods : Semen samples were collected from 144 infertile male, 35 normal fertile male ,seminal plasma was used for detection of chlamydia antibodies by Microimmunofluorescence test (MlF) using speciesspecific antigens (genital serotypes D-K) Results: This study confirmed that antichlamydia lgA and/ or lgG that were detected in seminal plasma of infertile males appeared to be C. trachomatis specific and associated with an inflammatory response. Semen parameters were severely affected in infertile patients with positive titer of antichlamydia lgA and or lgG that were detected in seminal plasma. Conclusions: chlamydia trachomatis play an important role in male infertility
منابع مشابه
O-5: The In vivo Effect of Chlamydial and Total Lipopolysaccharide on Semen Quality
Background: Lipopolysaccharide (LPS) is a major component of Chlamydia spp, and of all Gram-negative bacteria. The role of LPS in alteration of sperm parameters is controversial. In this study quantification of Chlamydia-specific and general lipopolysaccharide in semen was correlated to semen quality. Materials and Methods: 255 male partners of infertile couples were recruited to produce urine ...
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Background: Chlamydia Trachomatis (CT) is an obligate intracellular bacteria, that requires living cells to replicate itself and is responsible for lower urinary tract disease in men and women. It can cause urethritis, epididymitis, orchitis and complications such as chronic prostatitis in men. Chlamydia infections may also directly affect male fertility by damaging the sperm, because sperm par...
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Background: Chlamydia trachomatis(CT) is an obligate intracellular bacteria, requires living cells to replicate itself. CT infection can remain up to 4 years in the couple and affect their fertility. The relationship between CT and infertility is very important because most patients are asymptomatic and untreated. After infection with CT, NK activation signals begin through interactions of its ...
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